TAFA2/FAM19A2 蛋白, Human

The FAM19A2 protein plays a key role as a neurotrophic factor, actively promoting neuronal survival and various neurobiological functions. Its involvement is shown to have a critical impact on the maintenance and health of neurons, underscoring its potential significance in supporting neurological health. TAFA2/FAM19A2 Protein, Human is the recombinant human-derived TAFA2/FAM19A2 protein, expressed by E. coli , with tag free.

FAM19A2 蛋白作为神经营养因子，在促进神经元存活和促进各种神经生物学功能方面发挥着关键作用。它参与支持神经元的健康和持久性，强调了它在维持神经元健康方面的重要性。FAM19A2 作为神经营养因子的特征表明它在神经保护策略和神经系统内基本过程的调节中具有潜在的相关性。

1. The biological activity is determined by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. rHuTAFA-2; immobilized at 6-24 μg/mL on a 96 well plate; is able to significantly enhance neurite outgrowth.
2. Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED₅₀ this effect is 1.455-3.659 μg/mL, corresponding to a specific activity is > 273.30 units/mg.

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  Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED₅₀ for this effect is 3.659 μg/ml, corresponding to a specific activity is 273.30 units/mg.

Human

E. coli

Tag Free

Q8N3H0-1 (A31-H131)

338811  [NCBI]

ANHHKAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRVTH

11-15 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 2 × PBS, pH 7.4 or 40 mM PB, 300 mM NaCl, pH 6.8.

<1 EU/μg; determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.