TAGLN2 蛋白, Human (HEK293, C-His)

Expressed in HEK 293 cells with a C-His tag, the human isoform of TAGLN2 Protein shares similarity with transgelin, an early marker of differentiated smooth muscle. While its specific function remains unclear, TAGLN2 is proposed as a tumor suppressor. The gene has multiple transcript variants, contributing to its potential roles' complexity. TAGLN2 demonstrates ubiquitous expression, notably in the lung (RPKM 268.8), stomach (RPKM 231.0), and 25 other tissues, suggesting involvement in diverse physiological contexts across multiple organs. TAGLN2 Protein,Human (HEK 293, C-His) is the recombinant human-derived TAGLN2 protein,Human(HEK 293, C-His), expressed by HEK293 , with C-6*His labeled tag. The total length of TAGLN2 Protein,Human (HEK 293, C-His) is 199 a.a., with molecular weight of ~25-30 kDa.

TAGLN2 蛋白，特别是在带有 C-His 标签的 HEK 293 细胞中表达的人类亚型，与分化平滑肌的早期标记物转凝胶蛋白 (transgelin) 具有相似性。虽然 TAGLN2 的具体功能尚未最终确定，但建议其作为肿瘤抑制因子发挥作用。该基因表现出编码不同亚型的多种转录变体，从而导致其潜在作用的复杂性。该 TAGLN2 蛋白表现出普遍表达，在肺 (RPKM 268.8)、胃 (RPKM 231.0) 和 25 个其他组织中检测到显着水平。其广泛的表达模式表明参与多个器官的各种生理环境。

Human

HEK293

C-6*His

P37802/NP_003555 (M1-L199)

8407

MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL

Approximately 25-30 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.