Fetal-tau/0N3R 蛋白, Human (His)

Tau/0N3R protein is encoded by the Tau/0N3R gene and undergoes regulated alternative splicing to produce different mRNA species.Its expression varies in the nervous system according to the maturation and type of neurons.Fetal-tau/0N3R Protein, Human (His) is the recombinant human-derived Fetal-tau/0N3R protein, expressed by E.coli , with N-6*His labeled tag.

Tau/0N3R 基因编码微管相关蛋白 tau (MAPT)，该蛋白经历复杂的、受调控的选择性剪接，产生各种 mRNA。MAPT 转录本的表达在整个神经系统中有所不同，具体取决于神经元成熟阶段和特定神经元类型。MAPT 基因突变与多种神经退行性疾病有关，包括阿尔茨海默病、皮克病、额颞叶痴呆、皮质基底节变性和进行性核上性麻痹。Tau/0N3R 在大脑 (RPKM 70.2)、肾脏 (RPKM 12.0) 和其他两种组织中观察到偏向表达，因此 Tau/0N3R 在神经生理学中发挥着关键作用，并与多种神经病理状况相关。

Human

E. coli

N-6*His

P10636-2/NP_058525.1 (A2-L352)

4137

40-50 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 10% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.