1. 重组蛋白
  2. Others
  3. TCEB3 蛋白, Human (Sf9, His, Strep)

TCEB3 蛋白, Human (Sf9, His, Strep)

目录号: HY-P701514
产品使用指南

TCEB3,也称为 SIII,作为关键的转录延伸因子,促进 RNA 聚合酶 II 进展超出阻断位点。它与SIII调节亚基B和C相互作用形成elongin BC复合物,显着增强亚基A的转录活性。TCEB3 蛋白, Human (Sf9, His, Strep) 是重组的 TCEB3 蛋白,由 Sf9 insect cells 表达,带有 N-Strep, N-8*His 标签。TCEB3 蛋白, Human (Sf9, His, Strep) 全长 797 个氨基酸。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

TCEB3, also known as SIII, acts as a key transcription elongation factor that promotes RNA polymerase II progression beyond the blocking site. It interacts with SIII regulatory subunits B and C to form the elongin BC complex, which significantly enhances the transcriptional activity of subunit A. TCEB3 Protein, Human (Sf9, His, Strep) is the recombinant human-derived TCEB3 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of TCEB3 Protein, Human (Sf9, His, Strep) is 797 a.a., .

研究背景

TCEB3,也称为 SIII,作为通用转录延伸因子发挥作用,促进 RNA 聚合酶 II 转录延伸超出模板编码的阻止位点。亚基 A 的转录活性通过其与 SIII 调节亚基 B 和 C 形成的二聚体复合物(统称为 elongin BC 复合物)的相互作用而得到显着增强。TCEB3 在多亚基组装体中运作,包括 elongin BC 复合物(ELOB 和 ELOC)、elongin A/ELOA、RBX1 和 CUL5。在这种情况下,它对单泛素化 POLR2A 进行多泛素化,有助于转录过程的调节。

种属

Human

表达系统

Sf9 insect cells

标签

N-Strep;N-8*His

蛋白编号

Q14241 (H2-R798)

基因 ID

6924

蛋白结构
N-term
8*His-Strep
TCEB3 (H2-R798)
Accession # Q14241
C-term
同用名
ELOA (TCEB3); Elongin-A; EloA; Elongin 110 kDa subunit; RNA polymerase II transcription factor SIII subunit A1; SIII p110; Transcription elongation factor B polypeptide 3
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TCEB3 Protein, Human (Sf9, His, Strep) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
TCEB3 Protein, Human (Sf9, His, Strep)
目录号:
HY-P701514
需求量: