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  3. Testican 3/SPOCK3 蛋白, Mouse (HEK293, His)

Testican 3/SPOCK3 蛋白, Mouse (HEK293, His)

目录号: HY-P71352
产品使用指南

Testican 3/SPOCK3 蛋白可能参与不同的神经发生步骤,表明在神经细胞发育中具有多方面的作用。它通过 MT1-MMP 和 MT3-MMP 抑制前基质金属蛋白酶 2 (MMP-2) 加工,调节 MMP-2 活性。 Testican 3/SPOCK3 与其他蛋白质的相似性表明其干扰肿瘤侵袭。其综合功能强调了在神经发育中的重要性以及在调节与肿瘤侵袭相关的细胞外基质动力学方面的潜在参与。Testican 3/SPOCK3 蛋白, Mouse (HEK293, His) 是重组的 睾丸 3/SPOCK3 蛋白,由 HEK293 表达,带有 C-6*His 标签。Testican 3/SPOCK3 蛋白, Mouse (HEK293, His) 全长 414 个氨基酸,分子量为 58-60 kDa。

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描述

Testican 3/SPOCK3 Protein potentially participates in diverse neurogenesis steps, indicating a multifaceted role in neural cell development. It inhibits pro-matrix metalloproteinase 2 (MMP-2) processing by MT1-MMP and MT3-MMP, regulating MMP-2 activity. Testican 3/SPOCK3's similarity to other proteins suggests interference with tumor invasion. Its comprehensive functions underscore significance in neurodevelopment and potential involvement in regulating extracellular matrix dynamics related to tumor invasion. Testican 3/SPOCK3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Testican 3/SPOCK3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Testican 3/SPOCK3 Protein, Mouse (HEK293, His) is 414 a.a., with molecular weight of 58-60 kDa.

研究背景

Testican 3/SPOCK3 蛋白可能参与神经发生的不同步骤,表明其在神经细胞发育的复杂过程中发挥多方面的作用。此外,它还抑制 MT1-MMP 和 MT3-MMP 对前基质金属蛋白酶 2 (MMP-2) 的加工,表明在调节 MMP-2 活性方面具有调节功能。此外,正如与其他蛋白质的相似性所表明的那样,Testican 3/SPOCK3 可能会干扰肿瘤侵袭。 Testican 3/SPOCK3 的综合功能强调了其在神经发育过程中的重要性以及在与肿瘤侵袭相关的细胞外基质动力学调节中的潜在参与。

种属

Mouse

表达系统

HEK293

标签

C-6*His

蛋白编号

Q8BKV0-1 (A23-I436)

基因 ID
蛋白结构
N-term
SPOCK3 (A23-I436)
Accession # Q8BKV0-1
6*His
C-term
同用名
Testican-3; Spock3
氨基酸序列

AAAVAVAGGRSDGGNFLDEKQWLTTISQYDKEVGQWNKFRDEVEDDYFRTWNPGKPFDQALDPAKDPCLKTKCSRHKVCITQDAQTALCISHRRLTHSMKEVGGSHKQWRGLPSSTCKPCPIAYASPVCGSDGHSYSSQCKLEYQACVLGKQISIKCEGRCPCPSDKSMNIGRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKALLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELGSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVADCAIDFEISGDFASGDFREWTDDEGEEDDIMNDKDDIEDDDEDEGDDDDDGDVHDGYI

分子量

58-60 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Testican 3/SPOCK3 Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Testican 3/SPOCK3 Protein, Mouse (HEK293, His)
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HY-P71352
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