TFF3 蛋白, Human

TFF-3 Protein, Human is a regulatory peptide involved in mucosal protection and repair in the gastrointestinal tract.

人三叶因子 3 是一种调节肽，参与胃肠道粘膜保护和修复。TFF3 主要存在于小肠和大肠的粘液细胞中。TFF3 在 NEC 中也具有潜在的治疗作用^[1]。

The ED₅₀ is <10 μg/mL as measured by human MCF-7 cells, corresponding to a specific activity of >100 units/mg.

Human

E. coli

Tag Free

Q07654 (E22-F80)

7033  [NCBI]

EEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF

Approximately 6.6 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.

• [1]. Zhang BH, et al. The therapeutic effect of recombinant human trefoil factor 3 on hypoxia-induced necrotizing enterocolitis in immature rat. Regul Pept. 2003 Nov 15;116(1-3):53-60.  [Content Brief]