1. 重组蛋白
  2. Cytokines and Growth Factors
  3. TFF3 蛋白, Human (P. pastoris, His)

TFF3 蛋白, Human (P. pastoris, His)

目录号: HY-P700523
产品使用指南

TFF3 蛋白对于维持和修复肠粘膜至关重要,作为运动原促进上皮细胞移动。作为单体,TFF3 具有个体效应,而作为二硫键连接的同二聚体,它可增强细胞对肠壁完整性的反应。TFF3 的多方面性质强调了其在平衡胃肠道粘膜维护和修复方面的重要性。TFF3 蛋白, Human (P. pastoris, His) 是重组的 TFF3 蛋白,由 P. pastoris 表达,带有 N-6*His 标签。TFF3 蛋白, Human (P. pastoris, His) 全长 52 个氨基酸,分子量为 7.5 kDa。

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描述

TFF3 Protein is crucial for maintaining and repairing the intestinal mucosa, promoting epithelial cell mobility as a motogen. As a monomer, TFF3 has individual effects, while as a disulfide-linked homodimer, it enhances cellular responses for intestinal lining integrity. TFF3's multifaceted nature underscores its significance in balancing mucosal maintenance and repair in the gastrointestinal tract. TFF3 Protein, Human (P. pastoris, His) is the recombinant human-derived TFF3 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of TFF3 Protein, Human (P. pastoris, His) is 52 a.a., with molecular weight of 7.5 kDa.

研究背景

TFF3 蛋白在肠粘膜的维护和修复中发挥着关键作用,通过作为运动原促进上皮细胞的活动性,积极参与愈合过程。二硫键连接的同二聚体形式同时以单体和同二聚体形式存在,表明其功能具有潜在的协同增强作用。作为单体发挥作用时,TFF3 可能会发挥个体效应,而作为同源二聚体,它可能协同促进对肠内壁完整性和恢复至关重要的动态细胞反应。TFF3 的多方面性质强调了其在协调胃肠道内粘膜维护和修复的复杂平衡方面的重要性。

种属

Human

表达系统

P. pastoris

标签

N-6*His

蛋白编号

Q07654 (L29-V80)

基因 ID
蛋白结构
N-term
6*His
TFF3 (L29-V80)
Accession # Q07654
C-term
同用名
TFF3; trefoil factor 3 (intestinal); ITF; Polypeptide P1.B; TFI; HITF; trefoil factor 3, HITF, human intestinal trefoil factor; OTTHUMP00000109349; P1B; trefoil factor 3; hITF; hP1.B; Intestinal trefoil factor
氨基酸序列

LLSSSSAEEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGV

分子量

7.5 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TFF3 Protein, Human (P. pastoris, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TFF3 Protein, Human (P. pastoris, His)
目录号:
HY-P700523
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