TIGIT 蛋白, Cynomolgus (HEK293, His)

Ig-like domain-containing protein is a class of proteins that may be involved in protein–protein and protein–ligand interactions, therefore being involved in biological processes such as down-regulation of T cell activation or cardiac and neuronal development. TIGIT Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TIGIT protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIGIT Protein, Cynomolgus (HEK293, His) is 121 a.a., with molecular weight of 16-30 kDa.

含有免疫球蛋白样结构域的蛋白质是一类可能参与蛋白质-蛋白质和蛋白质-配体相互作用的蛋白质。一些包含免疫球蛋白样结构域的蛋白可与膜免疫球蛋白信号受体结合，通过与免疫球蛋白竞争结合下调 T 细胞活化，包含免疫球蛋白样结构域的蛋白如神经调节蛋白可通过 IgL 样结构域与肝素结合，促进心脏和神经元的发育^[1][2]。

Cynomolgus

HEK293

C-6*His

G7NXM4 (M89-P209)

/

MMTGTIETTGNISAKKGGSVILQCHLSSTMAQVTQVNWEQHDHSLLAIRNAELGWHIYPAFKDRVAPGPGLGLTLQSLTMNDTGEYFCTYHTYPDGTYRGRIFLEVLESSVAEHSARFQIP

16-30 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.