TKT 蛋白, Human (His)

TKT proteins are essential for catalyzing the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor. This process is facilitated by the formation of a covalent intermediate with the cofactor thiamine pyrophosphate. TKT Protein, Human (His) is the recombinant human-derived TKT protein, expressed by E. coli , with N-6*His labeled tag. The total length of TKT Protein, Human (His) is 622 a.a., .

TKT 蛋白对于催化二碳酮醇基团从酮糖供体向醛糖受体的转移至关重要。该过程通过与辅因子焦磷酸硫胺素形成共价中间体来促进。TKT 蛋白的酶活性在多种代谢途径中发挥着关键作用，包括磷酸戊糖途径和卡尔文循环。酮醇基团的转移是这些途径中的关键步骤，能够实现糖的转化以及能量生产和生物合成的重要中间体的生成。TKT 蛋白的功能对于维持代谢通量和促进细胞内碳水化合物代谢的整体平衡至关重要。

Human

E. coli

N-6*His

P29401 (E2-A623)

7086

Approximately 69.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.22 μm filtered solution of 50 mM HEPES, pH7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.