TMK 蛋白, Bacillus anthracis (His)

TMK proteins play a central role by catalyzing the phosphorylation of deoxythymidine monophosphate (dTMP), a key step in the synthesis of deoxythymidine triphosphate (dTTP). This process converts dTMP into deoxythymidine diphosphate (dTDP), an important intermediate in dTTP biosynthesis. TMK Protein, Bacillus anthracis (His) is the recombinant TMK protein, expressed by E. coli , with N-6*His labeled tag. The total length of TMK Protein, Bacillus anthracis (His) is 208 a.a., with molecular weight of ~25 kDa.

TMK 蛋白在催化脱氧胸苷一磷酸 (dTMP) 的磷酸化中发挥着至关重要的作用，这是脱氧胸苷三磷酸 (dTTP) 在从头途径和补救途径中合成的关键步骤。该酶促过程导致 dTMP 转化为脱氧胸苷二磷酸 (dTDP)，作为 dTTP 生物合成的重要中间体。TMK 蛋白参与促进这种磷酸化事件，强调了其在调节 dTTP（DNA 合成所必需的基本核苷酸）产生中的核心调节作用。对 TMK 蛋白参与这些途径的全面了解增强了我们对细胞核苷酸动力学的了解，从而有助于维持基因组稳定性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Others

E. coli

N-6*His

C3LJ02 (M1-L208)

45020070  [NCBI]

MKGLFVTIEGPEGSGKTTLIQSLLPYFEQKEQKVMATREPGGIAISEDIRTILHKQEYTMMEARTEALLYAAARRQHLVEKVMPALNEDYLVLCDRFIDSSLAYQGYARGLGMDKVFEINRFATEDCMPSLTIYLDIEPEVGLARIAKDAGREVNRLDMEDISFHKRVREGYLQVVERFSDRIVLVNADQPMEKLIEEVIQVIEDKLL

Approximately 25 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized a 0.2 μm filtered solution of 50 mM PBS, 300 mM NaCl, 5% trehalose, 5% mannitol and 0.01% Tween80, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.