Transthyretin/TTR 蛋白, Cynomolgus (HEK293, His)

Transthyretin (TTR) is a thyroid hormone-binding protein that may be involved in transporting thyroxine from the blood to the brain. As a homotetramer, TTR forms a dimer of dimers with a ligand-regulated central channel. Transthyretin/TTR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Transthyretin/TTR protein, expressed by HEK293 , with N-His, N-Myc labeled tag. The total length of Transthyretin/TTR Protein, Cynomolgus (HEK293, His) is 127 a.a., with molecular weight of ~18 kDa.

甲状腺素运载蛋白 (TTR) 是一种甲状腺激素结合蛋白，与甲状腺素从血液到大脑的运输有关。TTR 在结构上组织为同四聚体，形成二聚体的二聚体，其中亚基围绕能够容纳两个配体分子的中央通道组装。同源四聚体的复杂结构表明其在促进甲状腺激素转运方面具有功能性作用。此外，TTR 与 RBP4 相互作用，进一步凸显了它参与复杂的分子相互作用以及在甲状腺激素调节中的潜在作用。

Measured in a cell proliferation assay using A549 cells. The ED50 this effect is 1.794 ng/mL, corresponding to a specific activity is 5.57×10⁵ units/mg.

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  Measured in a cell proliferation assay using A549 cells. The ED₅₀ this effect is 1.794 ng/mL, corresponding to a specific activity is 5.57×10⁵ units/mg.

Cynomolgus

HEK293

N-His;N-Myc

Q8HXW1 (G21-E147)

101864775  [NCBI]

GPTGVDESKCPLMVKVLDAVRGSPAVNVAVNVFKKAADETWAPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKSLGISPFHEHAEVVFTANDSGPRHYTIAALLSPYSYSTTAVVTNPKE

Approximately 18 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4, 20% Glycerol.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.