1. 重组蛋白
  2. Cytokines and Growth Factors Biotinylated Proteins
  3. TSLP 蛋白, Cynomolgus (Biotinylated, HEK293, His)

TSLP 蛋白, Cynomolgus (Biotinylated, HEK293, His)

目录号: HY-P78047
产品使用指南

TSLP蛋白作为细胞因子,在免疫调节中发挥着关键作用。它诱导单核细胞释放 T 细胞吸引趋化因子,并显着促进 CD11c(+) 树突状细胞的成熟。TSLP 蛋白, Cynomolgus (Biotinylated, HEK293, His) 是重组的 TSLP 蛋白,由 HEK293 表达,带有 C-His 标签。TSLP 蛋白, Cynomolgus (Biotinylated, HEK293, His) 全长 131 个氨基酸,分子量为 23-26 kDa。

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描述

TSLP protein, as a cytokine, plays a key role in immune regulation. It induces monocytes to release T-cell attracting chemokines and significantly promotes the maturation of CD11c(+) dendritic cells. TSLP Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived TSLP protein, expressed by HEK293 , with C-His labeled tag. The total length of TSLP Protein, Cynomolgus (Biotinylated, HEK293, His) is 131 a.a., with molecular weight of 23-26 kDa.

研究背景

TSLP(胸腺基质淋巴细胞生成素)蛋白是一种具有多种免疫调节功能的细胞因子。它诱导单核细胞释放吸引 T 细胞的趋化因子,并促进 CD11c(+) 树突状细胞的成熟,在免疫反应的调节中发挥着至关重要的作用。众所周知,TSLP 通过直接激活肥大细胞来影响过敏性炎症,从而促进复杂的过敏反应网络。TSLP通过与CRLF2和IL7R组成的受体复合物相互作用发挥作用,TSLP与CRLF2/TSLPR的结合是招募IL7R形成高亲和力三元复合物的机制先决条件。这些相互作用凸显了 TSLP 影响免疫细胞行为的复杂分子机制,强调了其在免疫系统调节和过敏反应中的作用。

种属

Cynomolgus

表达系统

HEK293

标签

C-His

蛋白编号

A0A7N9CAT7 (Y29-Q159)

基因 ID
蛋白结构
N-term
TSLP (Y29-Q159)
Accession # A0A7N9CAT7
His
C-term
同用名
thymic stromal lymphopoietin; TSLP
分子量

23-26 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TSLP Protein, Cynomolgus (Biotinylated, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TSLP Protein, Cynomolgus (Biotinylated, HEK293, His)
目录号:
HY-P78047
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