1. 重组蛋白
  2. Ubiquitin Related Proteins
  3. Deubiquitinase
  4. Ubiquitin-Specific Protease
  5. Ubiquitin specific peptidase 53 (USP53)
  6. USP53 蛋白, Human

USP53 蛋白, Human

目录号: HY-P701428
产品使用指南

USP53 蛋白是紧密连接中的关键元素,对于听觉毛细胞的存活和听力功能的维持至关重要。尽管缺乏肽酶活性,USP53 的重要性因其与 TJP1:TJP2 异二聚体的相互作用而凸显,这表明 USP53 与紧密连接的分子结构有微妙的关系。这种相互作用强调了 USP53 对细胞存活和听觉过程的潜在影响。USP53 蛋白, Human 是重组的 USP53 蛋白,由 E. coli 表达,不带标签。USP53 蛋白, Human 全长 322 个氨基酸。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

USP53 protein, a critical element in tight junctions, is essential for the survival of auditory hair cells and the maintenance of hearing function. Although lacking peptidase activity, USP53's importance is highlighted by its interaction with the TJP1:TJP2 heterodimer, suggesting nuanced involvement in the molecular architecture of tight junctions. This interaction emphasizes USP53's potential impact on cellular survival and auditory processes. USP53 Protein, Human is the recombinant human-derived USP53 protein, expressed by E. coli , with tag free. The total length of USP53 Protein, Human is 322 a.a., .

研究背景

USP53 蛋白是紧密连接中的重要组成部分,可能通过调节紧密连接屏障特性和机械稳定性,在听毛细胞的存活和听力功能的维持中发挥着至关重要的作用。尽管缺乏肽酶活性,USP53 在听觉功能中的重要性通过其 C 末端区域介导的与异二聚体 TJP1:TJP2 的相互作用得到了强调。这种相互作用表明紧密连接的复杂分子结构有微妙的参与,强调了它对细胞存活和听觉过程的潜在影响。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

Q70EK8 (K30-P351)

基因 ID

54532

蛋白结构
N-term
USP53 (K30-P351)
Accession # Q70EK8
C-term
同用名
USP53; Inactive ubiquitin carboxyl-terminal hydrolase 53; Inactive ubiquitin-specific peptidase 53
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
USP53 Protein, Human
目录号:
HY-P701428
需求量: