2. NF-κB Autophagy Cell Cycle/DNA Damage Epigenetics Apoptosis Anti-infection
  3. IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Keap1-Nrf2
  4. Resveratrol

Resveratrol  (Synonyms: trans-Resveratrol; SRT501)

目录号: HY-16561G
产品使用指南

摩尔计算器

Resveratrol (trans-Resveratrol; SRT501) 是一种天然多酚，具有抗氧化，抗炎，保护心脏和抗癌的特性。 它的靶点广泛，如 mTOR、JAK、β-amyloid、Adenylyl cyclase、IKKβ、DNA polymerase。Resveratrol 也是一种特异性的 SIRT1 活化剂。Resveratrol 是有效的孕烷 X 受体 (PXR) 抑制剂。Resveratrol 是一种 Nrf2 激活剂，在小鼠模型中可以改善衰老相关的进行性肾损伤。Resveratrol 作用于内皮细胞促进 NO 产生。

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Resveratrol Chemical Structure

Resveratrol Chemical Structure

CAS No. : 501-36-0

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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Customer Review

Resveratrol 相关抗体

Top Publications Citing Use of Products

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IKK-α IKK-β IKK IKKε TBK1

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Sirtuin SIRT1 SIRT2 SIRT3 SIRT6 SIRT5 SIRT7

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].

IC50 & Target

Adenylyl cyclase

0.8 nM (IC50)

IKKβ

1 (IC50)

DNA polymerase α

3.3 μM (IC50)

DNA polymerase δ

5 μM (IC50)

体内研究
(In Vivo)

Resveratrol (trans-Resveratrol；SRT501) 以 50 mg/kg (195.5±124.8 mm3；P<0.05) 或 100 mg/kg 处理后，与载体处理动物 (315±94 mm3) 相比，平均肿瘤体积减小(81.7±70.5 mm3；P<0.001)。肿瘤体积与肿瘤质量之间存在良好的相关性[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

228.24

Formula

C14H12O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Resveratrol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Resveratrol (GMP)501-36-0trans-Resveratrol (GMP) SRT501 (GMP)IKKAutophagyMitophagySirtuinApoptosisBacterialFungalKeap1-Nrf2IκB kinaseI kappa B kinase Mitochondrial AutophagyInhibitorinhibitorinhibit

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