1. Cell Cycle/DNA Damage
  2. RAD51
  3. RI(dl)-2

RI(dl)-2 抑制 RAD51 的 D-loop 活性,IC50 值为 11.1 µM,并抑制同源重组 (HR) 活性,IC50 值为 3.0 µM。RI(dl)-2 抑制了 HR 介导的 DNA 双链断裂修复,并对不同癌细胞系敏感。

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RI(dl)-2 Chemical Structure

RI(dl)-2 Chemical Structure

CAS No. : 1902146-75-1

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RI(dl)-2 的其他形式现货产品:

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Other Forms of RI(dl)-2:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RI(dl)-2 blocks RAD51’s D-loop activity in biochemical systems with an IC50 value of 11.1 µM and inhibits homologous recombination (HR) activity with an IC50 value of 3.0 µM. RI(dl)-2 inhibits HR-mediated repair of DNA double strand breaks and sensitizes different cancer cell lines[1].

分子量

287.36

Formula

C19H17N3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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RI(dl)-2
目录号:
HY-126972
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