Riboflavin-5-Phosphate-¹³C₄,¹⁵N₂-1  (Synonyms: 维生素 B2-¹³C₄,¹⁵N₂-1; Vitamin B2-¹³C₄,¹⁵N₂-1; E101-¹³C₄,¹⁵N₂-1)

Riboflavin-5-Phosphate-¹³C₄,¹⁵N₂-1 is the ¹³C-labeled and ¹⁵N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

462.30

C₁₃¹³C₄H₂₁N₂¹⁵N₂O₉P

83-88-5

维生素B2-¹³C₄,¹⁵N₂-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]

  [2]. Long, Q., et al., Riboflavin biosynthetic and regulatory factors as potential novel anti-infective drug targets. Chem Biol Drug Des, 2010. 75(4): p. 339-47.  [Content Brief]

  [3]. Zempleni, J., J.R. Galloway, and D.B. McCormick, Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr, 1996. 63(1): p. 54-66.  [Content Brief]

  [4]. Bertollo, C.M., et al., Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models. Eur J Pharmacol, 2006. 547(1-3): p. 184-91.  [Content Brief]