2. Epigenetics
  3. MicroRNA
  4. rno-let-7f-1-3p antagomir

rno-let-7f-1-3p antagomir 是一种经过特殊化学修饰的成熟miRNA的互补单链，全链进行甲氧基修饰，在5'端和3'端分别有2个和4个硫代骨架修饰，并在3'端连接有高亲和性胆固醇修饰。miRNA antagomir通过特异性结合成熟miRNA，阻止miRNA与其靶基因的互补配对，从而抑制miRNA的功能。相比于miRNA inhibitor，miRNA antagomir在动物实验中具有更高的稳定性和抑制效果，更易通过细胞膜、组织间隙而富集于靶细胞。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

RNA, (GGAAGGCAAUAGAUUGUAU) (2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

rno-let-7f-1-3p antagomir Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 nmol ￥1580
1-2 weeks
20 nmol ￥3160
1-2 weeks

* Please select Quantity before adding items.

Customer Review

Other Forms of rno-let-7f-1-3p antagomir:

rno-let-7f-1-3p antagomir 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

rno-let-7f-1-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

分子量

7135.64

miRBase编号
成熟miRNA序列

CUAUACAAUCUAUUGCCUUCC

茎环结构ID

rno-let-7f-1

茎环结构序列

AUCAGAGUGAGGUAGUAGAUUGUAUAGUUGUGGGGUAGUGAUUUUACCCUGUUUAGGAGAUAACUAUACAAUCUAUUGCCUUCCCUGAG

种属

Rat, Alligator mississippiensis, Anolis carolinensis, Chrysemys picta, Pig, Python bivittatus, Taeniopygia guttata

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

rno-let-7f-1-3p antagomir 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

rno-let-7f-1-3p antagomirMicroRNAmiRNAInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
rno-let-7f-1-3p antagomir
目录号：
HY-RI04205A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z