2. Anti-infection
  3. RSV
  4. RSV-IN-6

RSV-IN-6 (Compound 53) 是一种靶向 M2-1 蛋白的抗 RSV 剂，对 RSV-A 和 RSV-B 的 EC50 分别为 4.4 μM 和1.3 μM。

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RSV-IN-6 Chemical Structure

RSV-IN-6 Chemical Structure

CAS No. : 2415152-41-7

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RSV-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC50 values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively[1].

IC50 & Target

EC50: 1.3 μM (RSV-B), 4.4 μM (RSV-A)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEp-2 CC50
> 100 μM
Compound: 53
Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay
Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay
[PMID: 32143992]
HEp-2 EC50
1.3 μM
Compound: 53
Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
[PMID: 32143992]
HEp-2 EC50
4.4 μM
Compound: 53
Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
[PMID: 32143992]
分子量

385.57

Formula

C19H19N3S3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RSV-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RSV-IN-62415152-41-7RSVRespiratory syncytial virusM2-1RSV-ARSV-BInhibitorinhibitorinhibit

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产品名称：
RSV-IN-6
目录号：
HY-150547
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