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  3. (S)-CPP sodium

(S)-CPP sodium 可作为支链 α-酮酸脱氢酶复合物 (BCKDC) 激酶(通常称为 BDK 或酮酸脱氢酶激酶)的抑制剂。作为 BCKDC 活性的负调节剂,(S)-CPP(IC50 为 6.3 μM)抑制 BDK 可激活复合物,并导致野生型小鼠血浆中亮氨酸/异亮氨酸和缬氨酸水平显著下降。

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(S)-CPP sodium Chemical Structure

(S)-CPP sodium Chemical Structure

CAS No. : 194979-70-9

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

(S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.

分子量

206.60

Formula

C9H8ClNaO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(S)-CPP sodium 相关分类

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  • Do most proteins show cross-species activity?

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