2. Anti-infection
  3. Bacterial
  4. SAAP 148

SAAP 148 是一种抗菌剂和抗生物膜剂，对抗生素耐药病原体具有抑制活性，LC50 为 0.8-12.8 μM。

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Custom Peptide Synthesis

SAAP 148 Chemical Structure

SAAP 148 Chemical Structure

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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SAAP 148 的其他形式现货产品:

Customer Review

Other Forms of SAAP 148:

SAAP 148 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SAAP 148 is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM[1].

体外研究
(In Vitro)

SAAP 148 在 PBS 和血浆中抑制 S. aureus 和 P. aeruginosa，LC99 分别为 1.6，1.6，12.8 和 12.8 μM[1]。
SAAP-148 (0.4-3.2 μM，2 h) 与细菌膜相互作用并使细胞膜透化，导致细菌死亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SAAP 148 相关抗体:
体内研究
(In Vivo)

SAAP-148 (30 mg of 0.125-2% w/w 软膏，涂抹在皮肤上，单剂量) 可以根除皮肤上的 Methicillin (HY-121544)-耐受的 S. aureus (MRSA) 和 A. baumannii，减轻小鼠模型中的擦伤皮肤感染，且无毒性 (2000 mg/kg)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Abraded skin infection in C57BL/6J mice model[1]
Dosage: 30 mg of 0.125-2% w/w ointment
Administration: apply on skin, single dose
Result: Eradicated MRSA and A. baumannii, attenuated abraded skin infection
分子量

3267.06

Formula

C157H261N49O27
Sequence

Ac-Leu-Lys-Arg-Val-Trp-Lys-Arg-Val-Phe-Lys-Leu-Leu-Lys-Arg-Tyr-Trp-Arg-Gln-Leu-Lys-Lys-Pro-Val-Arg-NH2
Sequence Shortening

Ac-LKRVWKRVFKLLKRYWRQLKKPVR-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SAAP 148 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAAP 148SAAP148SAAP-148BacterialC57BL/6J miceS. aureusP. aeruginosaA. baumanniiInhibitorinhibitorinhibit

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产品名称：
SAAP 148
目录号：
HY-P10233
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