1. Anti-infection
  2. SARS-CoV
  3. SARS-CoV-2-IN-20

SARS-CoV-2-IN-20 (Compound 1a) 是一种有效的 SARS-CoV-2 抑制剂,EC50 值为 6.5 μM。SARS-CoV-2-IN-20 具有研究感染性疾病的潜力。

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SARS-CoV-2-IN-20 Chemical Structure

SARS-CoV-2-IN-20 Chemical Structure

CAS No. : 1260244-33-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SARS-CoV-2-IN-20 (Compound 1a) is a potent inhibitor of SARS-CoV-2 with an EC50 of 6.5 μM. SARS-CoV-2-IN-20 has the potential for the research of infection diseases[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 CC50
21.58 μg/mL
Compound: 1
Cytotoxicity against human HepG2 cells assessed as reduction in cell number after 24 hrs by bioluminescence assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell number after 24 hrs by bioluminescence assay
[PMID: 29908437]
HepG2 CC50
21.6 μg/mL
Compound: 1
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay
[PMID: 30067360]
Vero C1008 CC50
21.2 μM
Compound: 1a
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
[PMID: 35571875]
分子量

378.51

Formula

C24H30N2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SARS-CoV-2-IN-20 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SARS-CoV-2-IN-20
目录号:
HY-146381
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