2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-IN-6

SARS-CoV-IN-6 (Compound 17) 是 SARS-CoV-1 和 SARS-CoV-2 RdRp 的抑制剂，对 SARS-CoV-2 RdRp 的 IC50 值为 7.8 μM。SARS-CoV-IN-6 可降低感染 SARS-CoV-1 和 SARS-CoV-2 复制子的单轮感染性颗粒 (SRIP) 的细胞病变效应，并抑制 SARS-CoV N 蛋白的表达，对基于 SARS-CoV-1 和 SARS-CoV-2 复制子的 SRIP 的 EC50 值分别为 0.12 µM 和 1.47 µM。

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SARS-CoV-IN-6 Chemical Structure

SARS-CoV-IN-6 Chemical Structure

CAS No. : 2244671-47-2

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SARS-CoV-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SARS-CoV-IN-6 (Compound 17) is an inhibitor of SARS-CoV-1 and SARS-CoV-2 RdRp, with an IC50 value of 7.8 μM against SARS-CoV-2 RdRp. SARS-CoV-IN-6 reduces cytopathic effects in cells infected with SARS-CoV-1 and SARS-CoV-2 replicon-based single-round infectious particles (SRIPs), and inhibits SARS-CoV N protein expression, with EC50 values of 0.12 µM for SARS-CoV-1 replicon-based SRIPs and 1.47 µM for SARS-CoV-2 replicon-based SRIPs[1].

分子量

447.53

Formula

C25H29N5O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SARS-CoV-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-IN-62244671-47-2SARS-CoVSARS coronavirusInhibitorinhibitorinhibit

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