2. Metabolic Enzyme/Protease NF-κB Immunology/Inflammation
  3. HMG-CoA Reductase (HMGCR) Reactive Oxygen Species
  4. Simvastatin acid ammonium (Standard)

Simvastatin acid ammonium (Standard)  (Synonyms: 辛伐他汀铵盐 (Standard))

目录号: HY-119695AR 纯度: ≥98%
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Simvastatin acid (ammonium) (Standard)是 Simvastatin acid (ammonium) 的分析标准品。本产品用于研究及分析应用。Simvastatin acid (Tenivastatin) ammonium 是一种有效的 HMG-CoA 还原酶 (HMGCR) 抑制剂。Simvastatin acid ammonium 降低吲哚酚硫酸盐 (Indoxyl sulfate) 介导的活性氧 (ROS) 产生。Simvastatin acid ammonium 也可调节心肌细胞和转染 OATP3A1 基因的 HEK293 细胞的 OATP3A1 表达。

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Simvastatin acid ammonium (Standard) Chemical Structure

Simvastatin acid ammonium (Standard) Chemical Structure

CAS No. : 139893-43-9

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生物活性

Simvastatin acid (ammonium) (Standard) is the analytical standard of Simvastatin acid (ammonium). This product is intended for research and analytical applications. Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

分子量

453.61

Formula

C25H43NO6
CAS 号
中文名称

辛伐他汀羟酸铵盐 (Standard)
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Simvastatin acid ammonium (Standard) 相关分类

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Keywords:

Simvastatin acid ammonium (Standard)139893-43-9辛伐他汀羟酸铵盐 (Standard)HMG-CoA Reductase (HMGCR)Reactive Oxygen SpeciescardiomyocytesHEK293hCMOATP3A1Inhibitorinhibitorinhibit

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