2. Metabolic Enzyme/Protease
  3. E1/E2/E3 Enzyme
  4. Skp2 inhibitor 3

Skp2 inhibitor 3 (E35) 是一种抗肿瘤剂，是一种强效的S期激酶相关蛋白2（SKP2）抑制剂，对 Skp2-Cks1 结合的 IC50 为4.86 μM。Skp2 inhibitor 3 (E35) 显著抑制克隆形成和迁移，并使细胞周期停滞在S期。

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Skp2 inhibitor 3 Chemical Structure

Skp2 inhibitor 3 Chemical Structure

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Skp2 inhibitor 3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Skp2 inhibitor 3 (E35), an antitumor agent, is a potent S‑Phase Kinase-associated Protein 2 (SKP2) inhibitor, with an IC50 of 4.86 μM for Skp2-Cks1 binding. Skp2 inhibitor 3 (E35) significantly inhibits colony formation and migration, as well as arrests the cell cycle at the S-phase[1].

IC50 & Target

IC50: 4.86 μM (Skp2-Cks1 binding)[1].
分子量

471.37

Formula

C21H19BrN4O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Skp2 inhibitor 3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Skp2 inhibitor 3E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligaseantitumorSKP2Cks1Inhibitorinhibitorinhibit

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产品名称：
Skp2 inhibitor 3
目录号：
HY-162938
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