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SN23862 是一种具有抗癌活性的肿瘤前药，是 CB-1954 (HY-13543) 的类似物。SN23862 可用于癌症研究。

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SN23862 Chemical Structure

SN23862 Chemical Structure

CAS No. : 142439-61-0

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SN23862 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SN23862 is a cancer prodrug with anti-cancer activity, and an analogue of CB-1954 (HY-13543). SN23862 can be used for cancer research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO-AA8 IC50
1450 μM
Compound: 1
Aerobic cytotoxic activity was evaluated by the growth inhibition of AA8 (chinese hamster) aerobic cells
Aerobic cytotoxic activity was evaluated by the growth inhibition of AA8 (chinese hamster) aerobic cells
[PMID: 9873426]
CHO-AA8 IC50
1600 μM
Compound: 2a
Compound was tested for aerobic growth inhibition against AA8 cells after 4 hr of exposure
Compound was tested for aerobic growth inhibition against AA8 cells after 4 hr of exposure
[PMID: 8691449]
CHO-AA8 IC50
470 μM
Compound: 6
Aerobic cytotoxicity was assessed in a growth inhibition assay using log phase cultures of the chinese hamster ovary fibroblast line AA8
Aerobic cytotoxicity was assessed in a growth inhibition assay using log phase cultures of the chinese hamster ovary fibroblast line AA8
[PMID: 8035424]
CHO-AA8 IC50
470 μM
Compound: 20
Growth inhibition of aerobic chinese hamster ovary fibroblast AA8 cell line using an exposure time of 18 hours
Growth inhibition of aerobic chinese hamster ovary fibroblast AA8 cell line using an exposure time of 18 hours
[PMID: 1507207]
EMT6 IC50
1.85 μM
Compound: 4
Antiproliferative activity against mouse EMT6 NTRpuro cells after 18 hrs
Antiproliferative activity against mouse EMT6 NTRpuro cells after 18 hrs
[PMID: 17326614]
EMT6 IC50
442 μM
Compound: 4
Antiproliferative activity against mouse wild type EMT6 NTR-ve cells after 18 hrs
Antiproliferative activity against mouse wild type EMT6 NTR-ve cells after 18 hrs
[PMID: 17326614]
SK-OV-3 IC50
> 1000 μM
Compound: 1
Aerobic cytotoxic activity was evaluated by the growth inhibition of SKOV (human ovarian cancer line) aerobic cells
Aerobic cytotoxic activity was evaluated by the growth inhibition of SKOV (human ovarian cancer line) aerobic cells
[PMID: 9873426]
UV4 IC50
108 μM
Compound: 20
Growth inhibition of aerobic chinese hamster ovary fibroblast UV4 cells using an exposure time of 18 hours
Growth inhibition of aerobic chinese hamster ovary fibroblast UV4 cells using an exposure time of 18 hours
[PMID: 1507207]
UV4 IC50
870 μM
Compound: 1
Aerobic cytotoxic activity was evaluated by the growth inhibition of UV4 aerobic cells
Aerobic cytotoxic activity was evaluated by the growth inhibition of UV4 aerobic cells
[PMID: 9873426]
V79 IC50
17 μM
Compound: 4
Antiproliferative activity against chinese hamster V79 NTRpuro cells after 18 hrs
Antiproliferative activity against chinese hamster V79 NTRpuro cells after 18 hrs
[PMID: 17326614]
V79 IC50
490 μM
Compound: 4
Antiproliferative activity against chinese hamster wild-type V79 NTR-ve cells after 18 hrs
Antiproliferative activity against chinese hamster wild-type V79 NTR-ve cells after 18 hrs
[PMID: 17326614]
WiDr IC50
703 μM
Compound: 4
Antiproliferative activity against human wild type WiDr NTR-ve cells after 18 hrs
Antiproliferative activity against human wild type WiDr NTR-ve cells after 18 hrs
[PMID: 17326614]
WiDr IC50
9.5 μM
Compound: 4
Antiproliferative activity against human WiDr NTRneo cells after 18 hrs
Antiproliferative activity against human WiDr NTRneo cells after 18 hrs
[PMID: 17326614]
分子量

351.14

Formula

C11H12Cl2N4O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SN23862 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SN23862142439-61-0SN 23862SN-23862Otherscancer prodruganti-cancerCB-1954 analogueInhibitorinhibitorinhibit

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产品名称：
SN23862
目录号：
HY-120313
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