2. Metabolic Enzyme/Protease
  3. Aldose Reductase
  4. SN34037

SN34037是一种特异性Aldo-keto还原酶1C3（AKR1C3，EC 1.1.1.188）抑制剂，具有抑制PR-104A的细胞毒活性。SN34037敏感的coumberone还原提供了一个快速且特异的AKR1C3活性检测方法。SN34037在高AKR1C3的TF1红白血病细胞中抑制了PR-104A的有氧细胞毒性，而在低AKR1C3的Nalm6前B细胞急性淋巴细胞白血病细胞中则没有这种抑制作用。

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SN34037 Chemical Structure

SN34037 Chemical Structure

CAS No. : 1548116-54-6

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SN34037 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SN34037 is a specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) with the ability to inhibit the cytotoxic activity of PR-104A. SN34037-sensitive coumberone reduction provides a rapid and specific assay for AKR1C3 activity. SN34037 inhibits the aerobic cytotoxicity of PR-104A in TF1 erythroleukemia cells with high AKR1C3 expression, but not in Nalm6 pre-B acute lymphoblastic leukemia cells with low AKR1C3 expression[1].

分子量

344.24

Formula

C15H19Cl2N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SN34037 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SN340371548116-54-6SN 34037SN-34037Aldose ReductaseInhibitorinhibitorinhibit

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