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  3. Solutol HS-15

Solutol HS-15  (Synonyms: 聚乙二醇12-羟基二醇; Polyethylene glycol 12-hydroxystearate)

目录号: HY-Y1893
COA 产品使用指南

Solutol HS-15, 一种 Macrogol 15 羟基硬脂酸酯,是一种通透性增强剂。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Solutol HS-15 Chemical Structure

Solutol HS-15 Chemical Structure

CAS No. : 61909-81-7

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 g ¥500
In-stock
50 g ¥800
In-stock
> 100 g   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Solutol HS-15, a Macrogol 15 hydroxy stearate, is a permeability enhancer[1].

体外研究
(In Vitro)

Solutol HS-15 用于增加生物制药分类系统 (BCS) 2 类和 4 类亲脂性分子的水溶性。Solutol HS-15 已显示出增强中型生物药物穿过上皮细胞的渗透性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

(C2H4O)nC18H36O3

CAS 号
性状

油状物

颜色

Colorless to off-white

中文名称

聚乙二醇12-羟基二醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

溶解性数据
细胞实验: 

Ethanol 中的溶解度 : 100 mg/mL (超声助溶)

H2O 中的溶解度 : 25 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料

参考文献
Cell Assay
[1]

For both MTS and LDH cell viability assays, cells are seeded at a density of 1×104 cells on 96-well plates and cultured for a minimum of 24 h. Solutol HS-15 (in 25 mM HBSS:HEPES, pH 7.4) solutions are applied at concentrations above and below the critical micelle concentration (CMC) (0.01 mM to 20 mM) and cytotoxicity is determined using the MTS and LDH assays. 25 mM HBSS:HEPES is used as a negative control and Triton-X 100 (3 mM) as a positive control. Following 3 h incubation, the MTS reagent in media and LDH working solution are added to the cells and the cells are incubated for a further 3 h at 37°C[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Solutol HS-15
目录号:
HY-Y1893
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