2. Apoptosis Cell Cycle/DNA Damage Autophagy Immunology/Inflammation
  3. FKBP
  4. SP3N

SP3N 是一个脯氨酸异构酶 FKBP12 的特异性降解剂，通过胺氧化酶代谢转化为活性醛类 (SP3CHO) 的前体，SP3CHO 募集 SCFFBXO22 连接酶进行 FKBP12 降解。SP3N 可用于癌症治疗中的研究。

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SP3N Chemical Structure

SP3N Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

SP3N 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SP3N is a specific degrader of proline isomerase FKBP12, which is metabolized by amine oxidase to a precursor of the active aldehyde (SP3CHO), which recruits SCFFBXO22 ligase for FKBP12 degradation. SP3N can be used in cancer therapy research[1].

分子量

727.88

Formula

C39H57N3O10
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SP3N 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SP3NFKBPFK506-binding proteinDegradersprecursorscancerFKBP12SCFFBXO22Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-161794
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