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Spinorphin  (Synonyms: LVV-hemorphin-4)

目录号: HY-P1044
产品使用指南

摩尔计算器

Spinorphin 是脑啡肽降解酶的抑制剂。Spinorphin 抑制氨基肽酶、二肽基氨基肽酶III、血管紧张素转换酶和脑非肽酶。Spinorphin 可用于缓解疼痛的研究。

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Spinorphin Chemical Structure

Spinorphin Chemical Structure

CAS No. : 137201-62-8

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Spinorphin 的其他形式现货产品:

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Other Forms of Spinorphin:

Spinorphin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Oocyte IC50
48.1 pM
Compound: 5, spinorphin
Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique
Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique
[PMID: 17676725]
Oocyte IC50
8.3 pM
Compound: 5, spinorphin
Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique
Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique
[PMID: 17676725]
分子量

877.04

Formula

C45H64N8O10
CAS 号
Sequence

Leu-Val-Val-Tyr-Pro-Trp-Thr
Sequence Shortening

LVVYPWT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Spinorphin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Spinorphin137201-62-8LVV-hemorphin-4OthersInhibitorinhibitorinhibit

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