2. Anti-infection
  3. Bacterial
  4. Fobrepodacin

Fobrepodacin  (Synonyms: SPR720; pVXc-486)

目录号: HY-135655A
产品使用指南

摩尔计算器

Fobrepodacin (SPR720) 是一种具有口服活性的，有效的 SPR719 (VXc-486; HY-12930) 磷酸盐前体。Fobrepodacin 在体内具有很好的杀菌 (bactericidal) 活性。

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Fobrepodacin Chemical Structure

Fobrepodacin Chemical Structure

CAS No. : 1384984-31-9

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Fobrepodacin 的其他形式现货产品:

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Fobrepodacin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fobrepodacin (SPR720) is an orally active and potent phosphate proagent of SPR719 (VXc-486; HY-12930). Fobrepodacin has potent bactericidal activities in vivo[1].

体内研究
(In Vivo)

Fobrepodacin (oral gavage; 10, 30, 100 mg/kg; once per day; 5 times per week for 4 weeks) reduces the mycobacterial burden in a model of chronic tuberculosis infection in mice[1].
Fobrepodacin (oral; 100 mg/kg; once per day; 5 days per week, for 8 weeks) improves the bactericidal activities of antimycobacterial drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Six-week old female BALB/c and C57BL/6 mice uninfected or M. tuberculosis-infected (Erdman)[1]
Dosage: 10, 30, 100 mg/kg
Administration: Oral gavage; once per day; 5 times per week for 4 weeks
Result: Reduced the mycobacterial burden in a model of chronic tuberculosis infection in mice.
Clinical Trial
分子量

508.44

Formula

C21H26FN6O6P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Fobrepodacin 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Fobrepodacin1384984-31-9SPR720 pVXc-486SPR 720SPR-720pVXc486pVXc 486pVXc-486BacterialorallyphosphateSPR719VXc-486Inhibitorinhibitorinhibit

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