1. JAK/STAT Signaling Stem Cell/Wnt
  2. STAT
  3. STAT3-IN-36

STAT3-IN-36 (compound 11g) 是一种靶向 LRPPRCSTAT3CDK1 的三靶点抑制剂,具有抗癌活性。STAT3-IN-36 可与 LRPPRC、STAT3 和 CDK1 结合,发挥比 TMF (HY-N6818) 或是 Capecitabine (HY-B0016) 更强的抑癌效果。STAT3-IN-36 对 HGC27 细胞的 IC50 为 1.8 μM。

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STAT3-IN-36 Chemical Structure

STAT3-IN-36 Chemical Structure

CAS No. : 3055766-74-7

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生物活性

STAT3-IN-36 (compound 11g) is a triple-target inhibitor targeting LRPPRC, STAT3, and CDK1 with anticancer activity. STAT3-IN-36 binds to LRPPRC, STAT3, and CDK1, exerting a stronger anticancer effect than TMF (HY-N6818) or Capecitabine (HY-B0016). STAT3-IN-36 inhibits HGC27 cells with IC50 1.8 μM.[1].

分子量

658.65

Formula

C30H24F2N2O9S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
STAT3-IN-36
目录号:
HY-168519
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