1. Metabolic Enzyme/Protease
  2. Steroid Sulfatase
  3. Steroid sulfatase/17β-HSD1-IN-4

Steroid sulfatase/17β-HSD1-IN-4 

目录号: HY-151202
产品使用指南

Steroid sulfatase/17β-HSD1-IN-4 (compound 37) 是一种类固醇硫酸酯酶 (STS) 和 17β-羟基类固醇脱氢酶 1 型 (17β HSD1) 双重抑制剂。Steroid sulfatase/17β-HSD1-IN-4 不可逆地抑制 hSTS 的活性,其 IC50 值为 63 nM。Steroid sulfatase/17β-HSD1-IN-4 可用于子宫内膜异位症及其他雌激素依赖性疾病的研究。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Steroid sulfatase/17β-HSD1-IN-4 Chemical Structure

Steroid sulfatase/17β-HSD1-IN-4 Chemical Structure

CAS No. : 2990549-94-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS activity with anIC50 value of 63 nM. Steroid sulfatase/17β-HSD1-IN-4 can be used in the study of endometriosis and other estrogen-dependent diseases[1].

IC50 & Target

IC50: 63 nM (hSTS)[1].

体外研究
(In Vitro)

Steroid sulfatase/17β-HSD1-IN-4 (compound 37) (0-1100 nM, 24 h) inhibits human steroid sulfatase (hSTS) with an IC50 value of 63 nM and acts on irreversible inhibition of hSTS with an IC50 value of 60 nM in T47D human breast cancer cells[1].
Steroid sulfatase/17β-HSD1-IN-4 (compound 37) (20 μM, 48 h) inhibits HEK-293 cells growth by 15.1% at a concentration of 20 μM with low cytotoxicity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

403.48

Formula

C18H17N3O4S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Steroid sulfatase/17β-HSD1-IN-4
目录号:
HY-151202
需求量: