2. Metabolic Enzyme/Protease
  3. Steroid Sulfatase
  4. Steroid sulfatase-IN-1

Steroid sulfatase-IN-1 是一种有效的且具有口服活性的 Steroid sulfatase 抑制剂，IC50 为 1.71 nM。Steroid sulfatase-IN-1 在体内发挥抗肿瘤作用。Steroid sulfatase-IN-1 具有乳腺癌研究潜力。

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Steroid sulfatase-IN-1 Chemical Structure

Steroid sulfatase-IN-1 Chemical Structure

CAS No. : 2403716-19-6

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Steroid sulfatase-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 nM. Steroid sulfatase-IN-1 shows antitumor activity in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer[1].

IC50 & Target

IC50: 1.71 nM (Steroid sulfatase)[1]
体内研究
(In Vivo)

Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity in Breast Carcinoma Model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 67NR mouse (Breast Carcinoma Model)[1]
Dosage: 50 mg/kg
Administration: P.o.
Result: Showed significant antitumor activity with the TGI value of 51%.
分子量

385.23

Formula

C14H10Cl2N4O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Steroid sulfatase-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Steroid sulfatase-IN-12403716-19-6Steroid SulfataseBreast Cancerantitumor67NR mouseorally activeestrogen levelInhibitorinhibitorinhibit

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