2. Immunology/Inflammation Anti-infection
  3. STING SARS-CoV
  4. STING agonist-30

STING agonist-30 是一种有效的 STING 激动剂。STING agonist-30 表现出 STING 依赖性免疫激活。STING agonist-30 对多种病毒具有广泛的抑制作用，包括单纯疱疹病毒 (HSV)、轮状病毒和严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2)。

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STING agonist-30 Chemical Structure

STING agonist-30 Chemical Structure

CAS No. : 2951078-67-2

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STING agonist-30 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

STING agonist-30 is a potent STING agonist. STING agonist-30 exhibits STING-dependent immune activation. STING agonist-30 has extensive inhibitory effects on various viruses, including the herpes simplex virus (HSV), rotavirus, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1].

体外研究
(In Vitro)

STING agonist-30 (compound 23; 20 μM; 5 h) 增加野生型 HT1080 细胞中的 TBK1 磷酸化，但不增加 HT1080 STING-KO 细胞中的 TBK1 磷酸化[1]。
STING agonist-30 (20 μM; 8 h) 增强干扰素 β (IFNβ) 和 TNF-α 的表达[1]。
STING agonist-30 (0-20 μM; 5 h) 以剂量依赖性方式激活小鼠和人类 STING[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

STING agonist-30 相关抗体:

Western Blot Analysis[1]

Cell Line: HT1080, THP1, BMDMs and MEFs
Concentration: 2.5, 5, 10, and 20 μM
Incubation Time: 5 hours
Result: Induced obvious dimeric STING bands.
分子量

380.31

Formula

C15H16N4O8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

STING agonist-30 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STING agonist-302951078-67-2STING agonist30STING agonist 30STINGSARS-CoVStimulator of Interferon GenesTMEM173MITAERISMPYSSARS coronavirusVirusesherpes simplex virussevere acute respiratory syndrome coronavirus 2Inhibitorinhibitorinhibit

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