1. 天然产物
  2. 植物 酚类
  3. 芍药科 多酚类
  4. 芍药
  5. Suffruticosol A

Suffruticosol A 是一种神经保护剂,能够恢复东莨菪碱诱导的细胞神经退行性损伤。Suffruticosol A 能够改善了海马体胆碱能缺陷,并部分增强 BDNF 信号传导。Suffruticosol A 在 Scopolamine (HY-N0296) 诱导模型中具有神经改善作用,可恢复小鼠的记忆和认知行为。Suffruticosol A 能从 P. lactiflora 的种子中分离得到。

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Suffruticosol A Chemical Structure

Suffruticosol A Chemical Structure

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Suffruticosol A is a neuroprotective agent that restores scopolamine-induced cellular neurodegenerative damage. Suffruticosol A ameliorates hippocampal cholinergic deficits and partially enhances BDNF signaling. Suffruticosol A has neuromodulatory effects in a Scopolamine (HY-N0296)-induced model, restoring memory and cognitive performance in mice. Suffruticosol A can be isolated from seeds of P. lactiflora[1].

IC50 & Target

BDNF[1]

体外研究
(In Vitro)

Suffruticosol A(20 μM;24 小时)可恢复人神经母细胞瘤 SH-SY5Y 细胞相对东莨菪碱 (2 mM) 处理的细胞活力和存活率[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Suffruticosol A(4 或 15 ng,每周两次;注射到大脑第三脑室)可改善东莨菪碱 (1.0 mg/kg;腹腔注射) 引起的小鼠模型认知和记忆损伤的神经元效应[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

682.71

Formula

C42H34O9

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Suffruticosol A
目录号:
HY-N11872
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