2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. TASP0412098

TASP0412098 是一种口服有效且选择性的 CRTH2/DP2 拮抗剂，具有高结合亲和力 (IC50 2.1 nM) 和功能活性 (IC50 12 nM)。在小鼠和豚鼠的支气管哮喘模型中，TASP0412098 具有抑制哮喘的潜在作用。

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TASP0412098 Chemical Structure

TASP0412098 Chemical Structure

CAS No. : 1233248-29-7

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TASP0412098 相关抗体

Top Publications Citing Use of Products

查看 Prostaglandin Receptor 亚型特异性产品:

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DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TASP0412098 is an orally available, potent and selective CRTH2/DP2 antagonist with high binding affinity (IC50 2.1 nM) and functional activity (IC50 12 nM). TASP0412098 has the potential to suppress asthma in mouse and guinea pig bronchial asthma models[1].

IC50 & Target

CRTH2/DP2[1]
分子量

458.94

Formula

C27H23ClN2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TASP0412098 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TASP04120981233248-29-7TASP 0412098TASP-0412098Prostaglandin ReceptorInhibitorinhibitorinhibit

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产品名称：
TASP0412098
目录号：
HY-117862
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