1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. TAT-CBD3A6K

TAT-CBD3A6K 是一种修饰的 TAT-CBD3 肽。TAT-CBD3A6K 减少背根神经节 (DRG) 神经元中的 T 型和 R 型电压依赖性钙电流。TAT-CBD3A6K 通过阻止 CRMP-2 介导的 T 型和 R 型钙通道功能增强,在 AIDS 诱导的周围神经病变模型中显示出抗伤害作用

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Custom Peptide Synthesis

TAT-CBD3A6K Chemical Structure

TAT-CBD3A6K Chemical Structure

CAS No. : 1505463-57-9

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250 mg   询价  

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TAT-CBD3A6K, is a modified TAT-CBD3 peptide. TAT-CBD3A6K reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. TAT-CBD3A6K shows anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function[1][2].

分子量

3249.83

Formula

C137H250N60O32

CAS 号
Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Arg-Ser-Arg-Leu-Lys-Glu-Leu-Arg-Gly-Val-Pro-Arg-Gly-Leu

Sequence Shortening

YGRKKRRQRRRARSRLKELRGVPRGL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TAT-CBD3A6K
目录号:
HY-P10358
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