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  3. Taurohyodeoxycholic acid-d4 sodium

Taurohyodeoxycholic acid-d4 sodium  (Synonyms: 牛磺去氧胆酸钠-d4)

目录号: HY-114360AS1
产品使用指南

Taurohyodeoxycholic acid-d4 (sodium)是氘代标记的Taurohyodeoxycholic acid (sodium)。Taurohyodeoxycholic acid (THDCA) sodium 是二级胆汁酸羟基去氧胆酸的牛磺酸共轭形式。Taurohyodeoxycholic acid 还能降低 TNBS 诱导的溃疡性结肠炎小鼠模型中髓过氧化物酶、TNF-α 和 IL-6 的活性和表达,以及抑制结肠损伤。

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Taurohyodeoxycholic acid-d<sub>4</sub> sodium Chemical Structure

Taurohyodeoxycholic acid-d4 sodium Chemical Structure

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规格 是否有货
1 mg 询价

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Other Forms of Taurohyodeoxycholic acid-d4 sodium:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium)[1]. Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Taurohyodeoxycholic acid 在体外可减小人胆结石的大小和重量。Taurohyodeoxycholic acid 增加大鼠胆汁流量、胆胆固醇分泌和胆脂分泌。Taurohyodeoxycholic acid 和 Taurochenodeoxycholic acid 联合给药可预防 Taurohyodeoxycholic acid 引起的肝毒性,增加大鼠胆汁流量、胆汁酸和磷脂分泌。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

499.70 (free acid)

Formula

C26H45NO6S.xNa

非标记 CAS

38411-85-7

中文名称

牛磺去氧胆酸钠-d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Taurohyodeoxycholic acid-d4 sodium
目录号:
HY-114360AS1
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