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  4. Terminal deoxyribonucleotidyltransferase

Terminal deoxyribonucleotidyltransferase  (Synonyms: 末端脱氧核糖核苷酸转移酶; TdT)

目录号: HY-E70016
COA 产品使用指南

Terminal deoxyribonucleotidyltransferase (TdT) 催化脱氧核糖核苷酸三磷酸缩合到 DNA 链的 3' 羟基末端,并在 V(D)J 重组期间将 N 区添加到基因片段连接处。Terminal deoxyribonucleotidyltransferase 在未成熟的、pre-B、pre-T 淋巴细胞和急性淋巴细胞白血病/淋巴瘤细胞中表达。

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Terminal deoxyribonucleotidyltransferase Chemical Structure

Terminal deoxyribonucleotidyltransferase Chemical Structure

CAS No. : 9027-67-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1].

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

末端脱氧核糖核苷酸转移酶

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Terminal deoxyribonucleotidyltransferase 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Terminal deoxyribonucleotidyltransferase
目录号:
HY-E70016
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