2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Tetraethylene glycol monotosylate

Tetraethylene glycol monotosylate  (Synonyms: Tos-PEG4)

目录号: HY-41541 纯度: ≥97.0%
COA 产品使用指南

摩尔计算器

Tetraethylene glycol monotosylate 是一种可降解 (cleavable) 的基于酰基腙的 ADC linker，用于合成抗体偶联活性分子 (ADCs)。Tetraethylene glycol monotosylate 也可用作 PROTAC 的 Linker，可用于 PROTAC 的合成。

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Tetraethylene glycol monotosylate Chemical Structure

Tetraethylene glycol monotosylate Chemical Structure

CAS No. : 77544-60-6

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规格 价格 是否有货 数量
100 mg ￥100
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250 mg ￥160
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1 g ￥400
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25 g ￥4349
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Tetraethylene glycol monotosylate 相关抗体

Top Publications Citing Use of Products

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target[1]

Cleavable Linker

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tetraethylene glycol monotosylate 相关抗体:
分子量

348.41

Formula

C15H24O7S
CAS 号
性状

粘稠液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥97.0%

COA (187 KB) HNMR (129 KB)

产品使用指南 (1538 KB)
参考文献

Tetraethylene glycol monotosylate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetraethylene glycol monotosylate77544-60-6Tos-PEG4ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerADCLinkerInhibitorinhibitorinhibit

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产品名称：
Tetraethylene glycol monotosylate
目录号：
HY-41541
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