2. Apoptosis
  3. Cuproptosis
  4. Tetrathiomolybdate

Tetrathiomolybdate 是一种口服有效的抗铜剂，能够降低体内铜含量。Tetrathiomolybdate 对小鼠胶原诱导关节炎具有保护作用。Tetrathiomolybdate 还能够降低体内血糖，但对遗传性糖尿病 (db/db) 的小鼠无影响。Tetrathiomolybdate 还抑制血管生成，对恶性胸膜间皮瘤也有抗血管生成作用。

该游离形式化合物不稳定，推荐具有相同生物学活性的稳定盐形式 Ammonium tetrathiomolybdate。

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Tetrathiomolybdate Chemical Structure

Tetrathiomolybdate Chemical Structure

CAS No. : 16330-92-0

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Tetrathiomolybdate 的其他形式现货产品:

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Tetrathiomolybdate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma[1][2][3].

体内研究
(In Vivo)

Tetrathiomolybdate (0.2 mg/小鼠/天; 口服; 10 周)保护小鼠免受胶原诱导的关节炎，具有预防作用[1]。
Tetrathiomolybdate (0.03 mg/mL; 加在水中，8 周)通过减少肿胀和红斑抑制小鼠胶原诱导关节炎的进展[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Collagen-induced arthritis model in mice[1]
Dosage: 0.2 mg/mouse/day or 0.03 mg/mL, added in water
Administration: Oral gavage, for 10 weeks; Collagen injected at weeks 2
Result: Showed significant preventive effect and protective effect in mice.
Clinical Trial
分子量

224.22

Formula

MoS42-
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tetrathiomolybdate 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tetrathiomolybdate16330-92-0CuproptosisInhibitorinhibitorinhibit

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