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  3. Thalidomide (Standard)

Thalidomide (Standard)  (Synonyms: 沙利度胺(Standard))

目录号: HY-14658R 纯度: ≥98%
产品使用指南

Thalidomide (Standard)是 Thalidomide 的分析标准品。本产品用于研究及分析应用。Thalidomide 能够抑制 cereblon (cullin-4 E3 泛素连接酶复合物 CUL4-RBX1-DDB1 的一部分),Kd 值约为 250 nM,具有免疫调节、抗炎、抗肿瘤作用。Thalidomide 可以作为分子胶来增强底物。

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Thalidomide (Standard) Chemical Structure

Thalidomide (Standard) Chemical Structure

CAS No. : 50-35-1

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10 mg ¥225
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50 mg ¥594
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100 mg ¥900
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生物活性

Thalidomide (Standard) is the analytical standard of Thalidomide. This product is intended for research and analytical applications. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.

分子量

258.23

Formula

C13H10N2O4

CAS 号
中文名称

沙利度胺(Standard)

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Thalidomide (Standard)
目录号:
HY-14658R
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