2. Protein Tyrosine Kinase/RTK
  3. Tie VEGFR
  4. TIE-2/VEGFR-2 kinase-IN-5

TIE-2/VEGFR-2 kinase-IN-5 是一个抗血管生成剂。TIE-2/VEGFR-2 kinase-IN-5 也是一种有效的 TIE-2 和 VEGFR-2 酪氨酸激酶受体抑制剂， pIC50 值分别为 7.78 nM 和 8.11 nM。TIE-2/VEGFR-2 kinase-IN-5 可用于血管生成的研究。

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TIE-2/VEGFR-2 kinase-IN-5 Chemical Structure

TIE-2/VEGFR-2 kinase-IN-5 Chemical Structure

CAS No. : 1014407-83-0

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TIE-2/VEGFR-2 kinase-IN-5 相关抗体

Top Publications Citing Use of Products

查看 Tie 亚型特异性产品:

查看所有亚型
Tie2

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent. TIE-2/VEGFR-2 kinase-IN-5 also is a potent TIE-2 and VEGFR-2 tyrosine kinase inhibitor with pIC50 values of 7.78 nM and 8.11 nM, respectively. TIE-2/VEGFR-2 kinase-IN-5 can be used for the research of angiogenesis[1].

IC50 & Target

Tie2

7.78 nM (IC50)

VEGFR-2

8.11 nM (IC50)

分子量

481.35

Formula

C21H13F6N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TIE-2/VEGFR-2 kinase-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TIE-2/VEGFR-2 kinase-IN-51014407-83-0TieVEGFRAngiopoietin receptorVascular endothelial growth factor receptorTIE-2VEGFR-2tyrosine kinaseangiogenesisInhibitorinhibitorinhibit

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