2. Protein Tyrosine Kinase/RTK
  3. Anaplastic lymphoma kinase (ALK)
  4. TL13-110

TL13-110 是 一种 TL13-112 (HY-123919) 的阴性对照，是一种有效的 ALK 抑制剂，IC50 为 0.34 nM。TL13-110 不会降解细胞中的 ALK。

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TL13-110 Chemical Structure

TL13-110 Chemical Structure

CAS No. : 2229037-09-4

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规格 价格 是否有货 数量
5 mg ￥8791
3 - 4 周
10 mg   询价  
50 mg   询价  

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Customer Review

TL13-110 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TL13-110 is a negative control for TL13-112 (HY-123919) and a potent ALK inhibitor with an IC50 of 0.34 nM. TL13-110 does not degrade ALK in cells[1].

IC50 & Target

IC50: 0.34 nM (ALK); 81 μM (Cereblon)[1]
体外研究
(In Vitro)

TL13-110 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC50 values of 9080 nM, 23.1 nM, 21.2 nM, and 480 nM, respectively.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

TL13-110 相关抗体:
分子量

988.59

Formula

C49H62ClN9O9S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TL13-110 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TL13-1102229037-09-4Anaplastic lymphoma kinase (ALK)Anaplastic lymphoma kinaseALK tyrosine kinase receptorCD246Cluster of differentiation 246negativecontrolAurora AFERPTK2RPS6KA1cereblonInhibitorinhibitorinhibit

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产品名称：
TL13-110
目录号：
HY-136195
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