2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase II inhibitor 19

Topoisomerase II inhibitor 19 

目录号: HY-162381
产品使用指南

摩尔计算器

Topoisomerase II inhibitor 19 (compound 5h) 是一种 DNA 嵌入剂和拓扑异构酶 II (topoisomerase II) 抑制剂（IC50 值为 0.34 μM）。Topoisomerase II inhibitor 19 会在 ctDNA 中诱导损伤。

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Topoisomerase II inhibitor 19 Chemical Structure

Topoisomerase II inhibitor 19 Chemical Structure

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Topoisomerase II inhibitor 19 相关抗体

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA[1].

IC50 & Target[1]

Topoisomerase II

0.34 μM (IC50)

体外研究
(In Vitro)

Topoisomerase II inhibitor 19 (compound 5h; 24h) 通过将细胞周期阻滞在 S 期来抑制 MCF-7 细胞的细胞增殖[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Topoisomerase II inhibitor 19 相关抗体:
分子量

465.95

Formula

C27H16ClN3OS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Topoisomerase II inhibitor 19 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 19Topoisomerase II inhibitor19Topoisomerase II inhibitor-19TopoisomeraseDNA intercalatortopoisomerase IIcell cycle arrestInhibitorinhibitorinhibit

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