2. Immunology/Inflammation
  3. Thrombopoietin Receptor
  4. Totrombopag

Totrombopag 是一种口服有效的血小板生成素受体 (TpoR) 激动剂。Totrombopag 通过激活 TpoR，启动一个由 JAK2 激酶和转录因子 Stat5 介导的细胞内信号级联反应，这种信号传导过程是调节巨核细胞生长和分化成血小板的主要机制。Totrombopag 可以用于研究血小板生成和巨核细胞生物学。

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Totrombopag Chemical Structure

Totrombopag Chemical Structure

CAS No. : 376592-42-6

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规格 价格 是否有货
1 mg ￥2820
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5 mg 现货 询问价格 & 货期
10 mg 现货 询问价格 & 货期

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Other Forms of Totrombopag:

Totrombopag 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Totrombopag is an orally effective thrombopoietin receptor (TpoR) agonist. By activating TpoR, Totrombopag initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5, a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag can be used to study platelet production and megakaryocyte biology[1].

分子量

466.49

Formula

C25H22N8O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Totrombopag 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Totrombopag376592-42-6Thrombopoietin Receptorthrombopoietin receptoragonistJAK2STAT5megakaryocyte biologyInhibitorinhibitorinhibit

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产品名称：
Totrombopag
目录号：
HY-14756
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