1. Others Apoptosis Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Biochemical Assay Reagents Apoptosis Reactive Oxygen Species
  3. TPP-Ce6

TPP-Ce6 是一种线粒体靶向的光敏剂,由叶绿素e6 (Ce6) 通过酯键与三苯基膦 (TPP) 结合而成。TPP-Ce6 在光线照射下能够产生 ROS,尤其是单线态氧,这些 ROS 能够诱导氧化应激,导致线粒体功能障碍和细胞凋亡 (apoptosis)。TPP-Ce6 可用于线粒体在细胞凋亡 (apoptosis) 和能量代谢以及癌症治疗方面的研究。

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TPP-Ce6 Chemical Structure

TPP-Ce6 Chemical Structure

CAS No. : 3030629-73-0

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  • 生物活性

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生物活性

Tpp-ce6 is a mitochondria-targeting photosensitizer formed by binding chlorophyll e6 (Ce6) to triphenylphosphine (TPP) via an ester bond. TPP-Ce6 can produce ROS under light irradiation, especially singlet oxygen, which can induce oxidative stress, leading to mitochondrial dysfunction and apoptosis. TPP-Ce6 can be used in the study of mitochondria in apoptosis and energy metabolism as well as cancer therapy[1].

分子量

1464.66

Formula

C94H90N4O6P33+

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TPP-Ce6
目录号:
HY-158189
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