1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 49

Tubulin inhibitor 49 (Compound 18) 是微管蛋白聚合 (tubulin polymerization) 抑制剂,IC50为 48 μM。Tubulin inhibitor 49 可破坏细胞微管网络,在 G2 期阻滞细胞周期,并表现出细胞毒性(在 HeLa 细胞中 IC50=8.8 μM)。

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Tubulin inhibitor 49 Chemical Structure

Tubulin inhibitor 49 Chemical Structure

CAS No. : 1023875-75-3

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  • 生物活性

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生物活性

Tubulin inhibitor 49 (Compound 18) is an inhibitor for tubulin polymerization with an IC50 of 48 μM. Tubulin inhibitor 49 disrupts the cell microtubule network, arrests the cell cycle at G2 phase, and exhibits cytotoxicity (IC50=8.8 μM in HeLa cell)[1].

分子量

377.38

Formula

C18H14F3N3OS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Tubulin inhibitor 49 相关分类

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Tubulin inhibitor 49
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HY-169882
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