2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin polymerization-IN-18

Tubulin aggregation-IN-18 (compound 3) 是一种有效的 tubulin 聚合抑制剂。Tubulin aggregation-IN-18 具有研究乳腺癌和耐药结肠癌的潜力。

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Tubulin polymerization-IN-18 Chemical Structure

Tubulin polymerization-IN-18 Chemical Structure

CAS No. : 1258011-23-2

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Tubulin polymerization-IN-18 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tubulin polymerization-IN-18 (compound 8) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-18 has the potential for the research of breast cancers and chemoresistant colon cancers[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Epithelial cell IC50
10 mM
Compound: 35
Cytotoxicity against in CD1 mouse mammary epithelial cells after 72 hrs by alamar blue dye assay
Cytotoxicity against in CD1 mouse mammary epithelial cells after 72 hrs by alamar blue dye assay
[PMID: 21080725]
MCF7 IC50
0.0096 μM
Compound: 35
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
[PMID: 21080725]
MDA-MB-231 IC50
0.0288 μM
Compound: 35
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
[PMID: 21080725]
分子量

435.47

Formula

C25H25NO6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tubulin polymerization-IN-18 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-181258011-23-2Microtubule/Tubulintubulin polymerizationbreastchemoresistant colonInhibitorinhibitorinhibit

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