2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Tubulin polymerization-IN-65

Tubulin polymerization-IN-65 是一种微管蛋白聚合 (tubulin polymerisation) 抑制剂，具有广谱的细胞毒性。Tubulin polymerization-IN-65 诱导 G2 + M 细胞周期停滞。

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Tubulin polymerization-IN-65 Chemical Structure

Tubulin polymerization-IN-65 Chemical Structure

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Tubulin polymerization-IN-65 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tubulin polymerization-IN-65 is a tubulin polymerisation inhibitor with a broad spectrum cytotoxic. Tubulin polymerization-IN-65 induces G2 + M cell cycle arrest[1].

体外研究
(In Vitro)

Tubulin polymerization-IN-65（化合物 64；5 μM；24 小时）诱导 G2 + M 细胞周期停滞[1]。
Tubulin polymerization-IN-65 (72 小时) 抑制 HT29、U87、MC-7、A2780、H460、A431、Du145、BE2-C、SJ-G2、MIA、MCF10A 的细胞生长，GI50 分别为 0.26 μM、1.4 μM、0.35 μM、0.33 μM、0.42 μM、0.33 μM、0.90 μM、0.31 μM、0.79 μM、0.37 μM 和 0.56 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tubulin polymerization-IN-65 相关抗体:

Cell Cycle Analysis[1]

Cell Line: MIA pancreatic cancer cells
Concentration: 5 μM
Incubation Time: 24 h
Result: Induced G2 + M cell cycle arrest.
分子量

278.31

Formula

C17H14N2O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tubulin polymerization-IN-65 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-65Microtubule/Tubulintubulin polymerisation inhibitorsub micromolar cytotoxicityG2 + M cell cycle arrestInhibitorinhibitorinhibit

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产品名称：
Tubulin polymerization-IN-65
目录号：
HY-161763
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